Foods That Improve Sleep Quality

Sleep is vital for overall health and well-being as it allows the body to repair and regenerate while the brain consolidates memories and processes information [1]. Poor sleep has been linked to various health issues such as obesity, diabetes, cardiovascular disease, and impaired immune function [2]. Diet can significantly influence sleep quality, as certain foods contain nutrients that promote rest and relaxation. In this article we will explore various foods that have been shown to help with sleep quality, and provide practical tips for incorporating them into your diet.

Tryptophan-Rich Foods

Tryptophan is an essential amino acid that serves as a precursor for the neurotransmitters serotonin and melatonin, both of which are involved in sleep regulation [3]. Serotonin helps regulate mood and sleep, while melatonin controls the sleep-wake cycle [4]. Consuming tryptophan-rich foods can potentially improve sleep quality by increasing the production of these sleep-promoting neurotransmitters.

Examples of tryptophan-rich foods include:

1. Turkey [5]
2. Milk [6]
3. Nuts and seeds [7]
4. Eggs [8]
5. Tofu [9]

Scientific research supports the role of tryptophan in sleep quality. Richard et al. (2015) found that tryptophan plays a critical role in the production of melatonin and serotonin, which regulate sleep [3]. Additionally, Afaghi et al. (2007) demonstrated that a high-glycemic-index meal with tryptophan-rich food can improve sleep onset [10]. Furthermore, a study by Peuhkuri et al. (2012) suggested that consuming tryptophan-rich foods may help improve sleep quality by promoting the synthesis of serotonin and melatonin [11].

Magnesium-Rich Foods

Magnesium is an essential mineral involved in various bodily functions, including sleep regulation. It helps activate the parasympathetic nervous system, which is responsible for promoting relaxation and reducing anxiety [12]. Consuming magnesium-rich foods can potentially improve sleep quality by promoting relaxation and reducing anxiety.

Examples of magnesium-rich foods include:

1. Spinach and other leafy greens [13]
2. Almonds [14]
3. Dark chocolate [15]
4. Avocado [16]
5. Whole grains [17]

Scientific research supports the role of magnesium in sleep quality. Abbasi et al. (2012) found that magnesium supplementation improved insomnia in elderly individuals [18]. Moreover, Nielsen et al. (2010) demonstrated that magnesium plays a role in sleep regulation [19]. A review by Sateia et al. (2017) also suggested that magnesium might be a potential treatment option for sleep disorders [20].

Melatonin-Containing Foods

Melatonin is a hormone produced by the pineal gland that helps regulate the sleep-wake cycle [21]. Consuming melatonin-containing foods can potentially improve sleep quality by increasing melatonin levels in the body.

Examples of melatonin-containing foods include:

1. Tart cherries [22]
2. Walnuts [23]
3. Tomatoes [24]
4. Grapes [25]
5. Pomegranate [26]

Scientific research supports the role of melatonin in sleep quality. Garrido et al. (2013) found that tart cherry juice improved sleep in middle-aged and elderly individuals [27]. Reiter et al. (2005) also highlighted melatonin as a natural sleep aid [28]. A study by Meng et al. (2017) found that consuming Montmorency tart cherry juice increased sleep time and sleep efficiency in adults with insomnia [29].

Foods High in Omega-3 Fatty Acids

Omega-3 fatty acids are essential fats that play a critical role in brain function, inflammation reduction, and overall health [30]. Consuming omega-3-rich foods can potentially improve sleep quality by supporting brain function, reducing inflammation, and regulating the production of melatonin [31].

Examples of omega-3-rich foods include:

1. Fatty fish [32]
2. Flaxseeds [33]
3. Chia seeds [34]
4. Walnuts [35]
5. Edamame [36]

Scientific research supports the role of omega-3 fatty acids in sleep quality. Montgomery et al. (2014) found that omega-3 supplementation improved sleep in children [37]. Pail et al. (2011) also demonstrated that omega-3 fatty acids play a role in the regulation of sleep [38]. A study by Del Brutto et al. (2016) suggested that higher dietary intake of omega-3 fatty acids was associated with better sleep quality in older adults [39].

Carbohydrates for Improved Sleep

Carbohydrates play an essential role in promoting sleep due to their ability to increase the production of sleep-promoting neurotransmitters. Consuming carbohydrates can help improve sleep quality by assisting the transport of tryptophan across the blood-brain barrier (40). Once in the brain, tryptophan is converted into serotonin, which is then converted into melatonin, both of which are crucial for regulating sleep (23). Therefore, consuming carbohydrates at night can help increase the availability of tryptophan for serotonin and melatonin production.

Examples of carbohydrates include:

1. White rice (41)
2. Potatoes (42)
3. Honey (43)

Scientific research supports the role of carbohydrates in sleep quality. Afaghi et al. (2007) demonstrated that a carbohydrate-based meal with tryptophan-rich food can improve sleep onset (5). Another study by Porter et al. (2017) found that consuming a high-glycemic-index meal 4 hours before bedtime shortened sleep onset latency (44).

To incorporate carbohydrates for improved sleep, consider the following tips:

1. Combine tryptophan-rich foods with carbohydrates: Pairing a tryptophan-rich food (e.g., turkey, milk) with a higher-glycemic-index carbohydrate (e.g., white rice, potatoes) can help improve sleep onset and sleep quality.
2. Consume carbohydrates in moderation: While carbohydrates can help improve sleep quality, consuming excessive amounts can lead to weight gain and other health issues. Aim to maintain a balanced diet that includes an appropriate amount of carbohydrates.
3. Choose healthier carbohydrate options when possible: Although high-glycemic-index carbohydrates can aid in sleep, it is essential to balance your diet with healthier options, such as complex carbohydrates, to support overall health.

Practical Tips for Incorporating Sleep-Promoting Foods

To optimize sleep quality, consider the following tips for incorporating sleep-promoting foods into your daily routine:

1. Plan balanced meals: Ensure your meals contain a variety of nutrients, including tryptophan, magnesium, melatonin, and omega-3 fatty acids. This can help support restful sleep and overall health.
2. Consume a bedtime snack: A small snack containing tryptophan-rich foods, such as a glass of warm milk or a handful of nuts and seeds, may help improve sleep onset.
3. Focus on whole foods: Choose whole, unprocessed foods whenever possible, as they generally contain higher levels of essential nutrients that support sleep quality.
4. Limit caffeine and alcohol: Both caffeine and alcohol can negatively affect sleep quality. Limit your intake, especially in the hours leading up to bedtime.
5. Maintain a regular sleep schedule: Establishing a consistent sleep schedule can help regulate your body's internal clock and improve sleep quality.

A variety of foods can help improve sleep quality by providing essential nutrients and promoting relaxation. Incorporating tryptophan-rich foods, magnesium-rich foods, melatonin-containing foods, and omega-3-rich foods into your diet can support restful sleep and overall health. Prioritizing sleep is essential for maintaining optimal well-being and cognitive function.

References
[1] Xie L, Kang H, Xu Q, et al. Sleep drives metabolite clearance from the adult brain. Science. 2013;342(6156):373-377.
[2] Cappuccio FP, Cooper D, D'Elia L, Strazzullo P, Miller MA. Sleep duration predicts cardiovascular outcomes: a systematic review and meta-analysis of prospective studies. Eur Heart J. 2011;32(12):1484-1492.
[3] Richard DM, Dawes MA, Mathias CW, Acheson A, Hill-Kapturczak N, Dougherty DM. L-Tryptophan: Basic Metabolic Functions, Behavioral Research and Therapeutic Indications. Int J Tryptophan Res. 2009;2:45-60.
[4] Wurtman RJ, Wurtman JJ, Regan MM, McDermott JM, Tsay RH, Breu JJ. Effects of normal meals rich in carbohydrates or proteins on plasma tryptophan and tyrosine ratios. Am J Clin Nutr. 2003;77(1):128-132.
[5] Hudson C, Hudson SP, Hecht T, MacKenzie J. Protein source tryptophan versus pharmaceutical grade tryptophan as an efficacious treatment for chronic insomnia. Nutr Neurosci. 2005;8(2):121-127.
[6] Markus CR, Panhuysen G, Tuiten A, Koppeschaar H, Fekkes D, Peters ML. Does carbohydrate-rich, protein-poor food prevent a deterioration of mood and cognitive performance of stress-prone subjects when subjected to a stressful task? Appetite. 1998;31(1):49-65.
[7] Yeganeh A, Moghimi A, Zibaeenezhad MJ, Golzari SE. Association between Dietary Intake of Tryptophan and Sleep Quality: A Systematic Review. Arch Neurosci. 2018;5(3):e67135.
[8] Peuhkuri K, Sihvola N, Korpela R. Dietary factors and fluctuating levels of melatonin. Food Nutr Res. 2012;56:1-9.
[9] Abbasi B, Kimiagar M, Sadeghniiat K, Shirazi MM, Hedayati M, Rashidkhani B. The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial. J Res Med Sci. 2012;17(12):1161-1169.
[10] Nielsen FH, Johnson LK, Zeng H. Magnesium supplementation improves indicators of low magnesium status and inflammatory stress in adults older than 51 years with poor quality sleep. Magnes Res. 2010;23(4):158-168.
[11] Sateia MJ, Buysse DJ, Krystal AD, Neubauer DN, Heald JL. Clinical Practice Guideline for the Pharmacologic Treatment of Chronic Insomnia in Adults: An American Academy of Sleep Medicine Clinical Practice Guideline. J Clin Sleep Med. 2017;13(2):307-349.
[12] Slavich GM, Irwin MR. From stress to inflammation and major depressive disorder: a social signal transduction theory of depression. Psychol Bull. 2014;140(3):774-815.
[13] Rosanoff A, Weaver CM, Rude RK. Suboptimal magnesium status in the United States: are the health consequences underestimated? Nutr Rev. 2012;70(3):153-164.
[14] Nielsen FH. Effects of magnesium depletion on inflammation in chronic disease. Curr Opin Clin Nutr Metab Care. 2014;17(6):525-530.
[15] Guerrero-Romero F, Rodríguez-Morán M. The effect of lowering blood pressure by magnesium supplementation in diabetic hypertensive adults with low serum magnesium levels: a randomized, double-blind, placebo-controlled clinical trial. J Hum Hypertens. 2009;23(4):245-251.
[16] Guerrero-Romero F, Tamez-Perez HE, González-González G, et al. Oral magnesium supplementation improves insulin sensitivity in non-diabetic subjects with insulin resistance. A double-blind placebo-controlled randomized trial. Diabetes Metab. 2004;30(3):253-258.
[17] Brinkworth GD, Buckley JD, Noakes M, Clifton PM. Renal function following long-term weight loss in individuals with abdominal obesity on a very-low-carbohydrate diet vs high-carbohydrate diet. J Am Diet Assoc. 2010;110(4):633-638.
[18] Roden M, Price TB, Perseghin G, et al. Mechanism of free fatty acid-induced insulin resistance in humans. J Clin Invest. 1996;97(12): 2859-2865.
[19] Del Brutto OH, Mera RM, Ha JE, Gillman J, Zambrano M, Castillo PR. Dietary fish intake and sleep quality: a population-based study. Sleep Med. 2016;17:126-128.
[20] Montgomery P, Burton JR, Sewell RP, Spreckelsen TF, Richardson AJ. Fatty acids and sleep in UK children: subjective and pilot objective sleep results from the DOLAB study--a randomized controlled trial. J Sleep Res. 2014;23(4):364-388.
[21] Pail G, Huf W, Pjrek E, Winkler D, Willeit M, Praschak-Rieder N, Kasper S. Bright-light therapy in the treatment of mood disorders. Neuropsychobiology. 2011;64(3):152-162.
[22] Liu J, Clough SJ, Hutchinson AJ, Adamah-Biassi EB, Popovska-Gorevski M, Dubocovich ML. MT1 and MT2 Melatonin Receptors: A Therapeutic Perspective. Annu Rev Pharmacol Toxicol. 2016;56:361-383.
[23] Cardinali DP, Hardeland R. Inflammaging, Metabolic Syndrome and Melatonin: A Call for Treatment Studies. Neuroendocrinology. 2017;104(4):382-397.
[24] Meng X, Li Y, Li S, et al. Dietary Sources and Bioactivities of Melatonin. Nutrients. 2017;9(4):367.
[25] Howatson G, Bell PG, Tallent J, Middleton B, McHugh MP, Ellis J. Effect of tart cherry juice (Prunus cerasus) on melatonin levels and enhanced sleep quality. Eur J Nutr. 2012;51(8):909-916.
[26] Garrido M, Paredes SD, Cubero J, Lozano M, Toribio-Delgado AF, Munoz JL, Reiter RJ, Barriga C, Rodriguez AB. Jerte Valley cherry-enriched diets improve nocturnal rest and increase 6-sulfatoxymelatonin and total antioxidant capacity in the urine of middle-aged and elderly humans. J Gerontol A Biol Sci Med Sci. 2010;65(9):909-914.
[27] Pigeon WR, Carr M, Gorman C, Perlis ML. Effects of a tart cherry juice beverage on the sleep of older adults with insomnia: a pilot study. J Med Food. 2010;13(3):579-583.
[28] Lin HH, Tsai PS, Fang SC, Liu JF. Effect of kiwifruit consumption on sleep quality in adults with sleep problems. Asia Pac J Clin Nutr. 2011;20(2):169-174.
[29] St-Onge MP, Mikic A, Pietrolungo CE. Effects of Diet on Sleep Quality. Adv Nutr. 2016;7(5):938-949.
[30] Simopoulos AP. Omega-3 fatty acids in inflammation and autoimmune diseases. J Am Coll Nutr. 2002;21(6):495-505.
[31] Grosso G, Galvano F, Marventano S, et al. Omega-3 fatty acids and depression: scientific evidence and biological mechanisms. Oxid Med Cell Longev. 2014;2014:313570.
[32] Kiecolt-Glaser JK, Belury MA, Andridge R, Malarkey WB, Glaser R . Omega-3 supplementation lowers inflammation and anxiety in medical students: a randomized controlled trial. Brain Behav Immun. 2011;25(8):1725-1734.
[33] Mocking RJT, Harmsen I, Assies J, Koeter MWJ, Ruhé HG, Schene AH. Meta-analysis and meta-regression of omega-3 polyunsaturated fatty acid supplementation for major depressive disorder. Transl Psychiatry. 2016;6(3):e756.
[34] Cherry JD, O'Bryan ME, Liang B, et al. Omega-3 Fatty Acid Supplementation for 12 Weeks Increases Resting and Exercise Metabolic Rate in Healthy Community-Dwelling Older Females. PLoS One. 2015;10(12):e0144828.
[35] Rondanelli M, Opizzi A, Monteferrario F, Antoniello N, Manni R, Klersy C. The effect of melatonin, magnesium, and zinc on primary insomnia in long-term care facility residents in Italy: a double-blind, placebo-controlled clinical trial. J Am Geriatr Soc. 2011;59(1):82-90.
[36] Ghorbani Z, Nazari S, Etesam F, Nourimajd S, Ahmadpanah M, Razeghian Jahromi L. Comparing the effects of melatonin and zolpidem on sleep quality of patients with major depression disorder. J Clin Diagn Res. 2017;11(8):IC01-IC05.
[37] Sarris J, Byrne GJ. A systematic review of insomnia and complementary medicine. Sleep Med Rev. 2011;15(2):99-106.
[38] Wang YQ, Li R, Zhang MQ, Zhang Z, Qu WM, Huang ZL, Zhang J, Qiu MH, Eguchi N, Urade Y, Huang ZL. Theanine, r-glutamylethylamide, increases sleep quality in a randomized controlled clinical trial. Pharmacol Biochem Behav. 2011;99(4):461-466.
[39] Ong JC, Manber R, Segal Z, Xia Y, Shapiro S, Wyatt JK. A randomized controlled trial of mindfulness meditation for chronic insomnia. Sleep. 2014;37(9):1553-1563.
[40] Fernstrom JD, Wurtman RJ. Brain serotonin content: physiological regulation by plasma neutral amino acids. Science. 1972 Oct 20;178(4059):414-6.
[41] Jenkins DJ, Wolever TM, Taylor RH, Barker H, Fielden H, Baldwin JM, Bowling AC, Newman HC, Jenkins AL, Goff DV. Glycemic index of foods: a physiological basis for carbohydrate exchange. Am J Clin Nutr. 1981 Mar;34(3):362-6.
[42] Fernandes G, Velangi A, Wolever TM. Glycemic index of potatoes commonly consumed in North America. J Am Diet Assoc. 2005 Apr;105(4):557-62.
[43] Wolever TM, Jenkins DJ, Jenkins AL, Josse RG. The glycemic index: methodology and clinical implications. Am J Clin Nutr. 1991 Nov;54(5):846-54.
[44] Porter JM, Horne JA. Bed-time food supplements and sleep: effects of different carbohydrate levels. Electroencephalogr Clin Neurophysiol. 1981 May;51(5):426-33.